DMPT, Nomoro ea CAS: 4337-33-1. E ntle ka ho fetisisantho e hohelang metsinghona joale!

DMPTtse tsejoang e le dimethyl-β-propiothetin, e fumaneha haholo dimeleng tsa lewatle le tsa halophytic tse phahameng. DMPT e na le phello e khothalletsang metabolism ea phepo e nepahetseng ea liphoofolo tse anyesang, likhoho le liphoofolo tsa metsing (litlhapi le li-shrimp). DMPT ke ntho e nang le phello e matla ka ho fetisisa ea ho hohela liphoofolo tsa metsing har'a metsoako eohle e tsejoang e nang le (CH) le lihlopha tsa S.

1. Mohloli oa DMPT

Dimethyl sulfide (DMS) e hlahisoang ke Polysipho - nia fastigata e tsoa haholo-holo hoDMPT, e leng mofani oa methyl o sebetsang hantle ho bolele, 'me molaoli ea ka sehloohong oa osmotic oa bolele le semela se bataletseng sa Spartina angelica le sona ke DMPT. Sekahare sa DMPT sea fapana har'a mefuta e fapaneng ea bolele, 'me sekahare sa mofuta o tšoanang oa bolele le sona sea fapana ka linako tse fapaneng tsa selemo. DMPT e ka potlakisa haholo ho fepa le ho hola ha litlhapi tse fapaneng tsa metsi a hloekileng. Tšusumetso e susumetsang ho fepa ea DMPT e fapane le lintho tse ling tse kang L-amino acid kapa nucleotide, 'me e na le litlamorao tse khothalletsang ho fepa le ho hola hoo e ka bang liphoofolong tsohle tsa metsing.

2.1 Ligand tse Sebetsang e le Li-Receptors tsa Tatso

Phuputso mabapi le li-receptor lithong tsa kutlo tsa lik'hemik'hale tsa tlhapi tse ka sebelisanang le lihlopha tsa (CH) S e ntse e se na letho. Ho tsoa liphethong tse teng tsa liteko tsa boitšoaro, ho ka hlahlojoa hore litlhapi li na le li-receptor tsa tatso tse ka sebelisanang le metsoako e tlase ea boima ba limolek'hule e nang le lihlopha tsa (CH), N -, le (CH2) 2S.

2.2 Jwalo ka mofani wa methyl

Lihlopha tsa (CH) le tsa S hoDMPTMolek'hule ke mehlodi ya dihlopha tsa methyl tse hlokahalang bakeng sa metabolism ya phepo ya diphoofolo. Ho na le mefuta e mmedi ya methyltransferases (EC2.1.1.3 le EC2.1.1.5) sebeteng sa diphoofolo e sebediswang ke diphoofolo (CH) le S.

Ho ile ha fumanoa hore mahloriso a DMPT le sekhahla sa ho ntšoa ha DMS liseleng tsa lehoatata li eketsehile ka keketseho ea letsoai sebakeng sa temo sa lehoatata le lengoang (Hymenonas carterae).

DMPTe ruisitsoe liseleng tsa li-mollusk tse ngata tsa phytoplankton, bolele, le li-mollusk tse tšoanang le li-clam le likorale, hammoho le li-krill le 'mele ea litlhapi. Iida et al. (1986) ba tiisitse hore litaba tsa DMPT le tlhahiso ea DMS litlhaping li amana hantle le litaba tsa DMPT lijong tsa tsona, ho bontša hore raese ea DMPT liphoofolong e tsoa ho leraba 'me e kena' meleng oa phoofolo ea motho ka ketane ea lijo libakeng tsa tlhaho tsa leoatle. Bolele bo ka hlahisa DMPT le ho bo bokella maemong a holimo (3-5 mmol/L) 'meleng. DMPT litlhaping le li-mollusk e haufi le maemo a tsona lijong, 'me mahloriso a DMPT a bontša mokhoa o fokotsehang ka tatellano ea bolele (1 mmol/L), li-mollusk (0.1 mmol/L), le litlhapi (0.01 mmol/L).

Mokhoa oa Fisioloji oaDMPTKetso

Lilemong tsa morao tjena, lipatlisiso li fumane hore DMPT e na le phello e khothalletsang boitšoaro ba ho fepa le kholo ea litlhapi tse fapaneng tsa leoatleng le tsa metsi a hloekileng, li-crustacean le li-shellfish, tse ka ntlafatsang bokhoni ba tsona ba ho loantša khatello ea maikutlo le boikoetliso, le ho eketsa li-enzyme tsa bohlokoa tsa methyl ea sehlopha se tlase sa mahloriso lijong. Ha ho sebelisoa sebete sa leoatle e le thepa ea liteko le metsoako e fapaneng e nang le (CH) le lihlopha tsa S e le li-substrate, ho fumanoe hore E C.2.1.1.3 le E Mosebetsi oa enzyme o phahame haholo ha DMPT e sebelisoa e le substrate.

3. Litlamorao tsa phepo ea DMPT liphoofolong tsa metsing

Metswako e mashome a mabedi e tlase ya dimolek'hule e nang le (CH) le dihlopha tsa S e sebedisitswe bakeng sa boitshwaro ba ho loma le diteko tsa electrophysiological metsing a lewatle le ditlhapi tsa metsi a hlwekileng. Ho fumanwe hore DMPT e na le phello e matla ka ho fetisisa ya ho kgothaletsa boitshwaro ba ho loma ba mefuta e meraro ya ditlhapi, ho kenyeletswa tuna ya metsi a hlwekileng, carp, le black crucian carp (Carassius auratus cuviera). E boetse e kgothaditse haholo boitshwaro ba ho fepa ba sea water true scale (Pagrus major) le dikala tse hlano (Seriola quinquera diata).

Kopanya DMPT le metsoako e meng e nang le sebabole ka tekanyo ea 1.0mmol/L. lijong tse fapaneng tsa liteko, 'me u nke sebaka sa sehlopha sa taolo ka metsi a hloekisitsoeng ho etsa liteko tsa karabelo ea phepo holim'a crucian carp. Liphetho li bontšitse hore lihlopheng tse 'ne tsa pele tsa liteko, sehlopha sa DMPT se ne se e-na le karolelano ea maqhubu a 126 a holimo ho feta sehlopha sa taolo; Tekong ea bobeli ea lihlopha tse 5, sehlopha sa DMPT se ne se phahame ka makhetlo a 262.6 ho feta sehlopha sa taolo. Tekong e bapisoang le glutamine, ho fumanoe hore ka tekanyo ea 1.0mmol/L.