Jwalo ka selelekela sa asiti ya butyric,tributyl glycerideke tlatsetso e ntle ea asiti ea butyric e nang le thepa e tsitsitseng ea 'mele le ea lik'hemik'hale, polokeho le litla-morao tse seng chefo. Ha e rarolle feela bothata ba hore asiti ea butyric e nkha hampe ebile e fetoha habonolo, empa hape e rarolla bothata ba hore asiti ea butyric e thata ho e eketsa ka ho toba ka mpeng le mala. E na le menyetla e mengata ea ts'ebeliso lefapheng la phepo ea liphoofolo. E le tlatsetso ea lijo,tributyl glyceridee ka sebetsa ka ho toba tsamaisong ea tšilo ea lijo ea liphoofolo, ea fana ka matla bakeng sa tsamaiso ea mala ea liphoofolo, ea ntlafatsa bophelo bo botle ba mala a liphoofolo, le ho laola ts'ebetso ea kholo le boemo ba bophelo bo botle ba liphoofolo.

1. Ntlafatsa tshebetso ya kgolo

Ho eketsoa hatributyl glycerideHo fepa ho sebelisitsoe haholo tlhahisong ea mefuta eohle ea liphoofolo. Ho eketsa tekanyo e loketseng ea tributyl glyceride lijong ho ka eketsa karolelano ea boima ba letsatsi le letsatsi ba liphoofolo tse lekiloeng, ho fokotsa karolelano ea lijo ho ea boima, le ho ntlafatsa ts'ebetso ea kholo ea liphoofolo. Palo e ekelitsoeng ke 0.075% ~ 0.250%.

2. Ntlafatsa bophelo bo botle ba mala

Tributyrine ka bapala karolo e mafolofolo bophelong ba mala a liphoofolo ka ho ntlafatsa sebopeho sa mala le sebopeho, ho laola ho leka-lekana ha limela tsa mala, ho ntlafatsa mokoallo oa mala le bokhoni ba antioxidant. Phuputso e fumane hore ho eketsa lefuba lijong ho ka eketsa tlhahiso ea protheine e tiileng ea mala, ho khothaletsa nts'etsopele ea mucosa ea mala, ho ntlafatsa ho sileha ha limatlafatsi tsa lijo, ho ntlafatsa bokhoni ba antioxidant, ho fokotsa bongata ba libaktheria tse kotsi ka har'a tsela ea mala le ho eketsa bongata ba libaktheria tse molemo, ho khothaletsa nts'etsopele ea mala a liphoofolo, le ho ntlafatsa bophelo ba mala a liphoofolo.

Ho na le lithuto tse ling tse bontšitseng hore ho eketsoa ha lefuba lijong ho ka ntlafatsa haholo ho sileha ha protheine e tala, mafura a tala le matla a likolobe tse ntšitsoeng matsoeleng, 'me ho sileha ha limatlafatsi tsa lijo ho amana haufi-ufi le bophelo bo botle ba mala a liphoofolo. Ho ka bonoa hore lefuba le khothalletsa ho monngoa le ho siloa ha limatlafatsi ka maleng.

Ho eketsatributyl glyceridee ka eketsa bophahamo ba villus le boleng ba V/C ba tsela ea mala ea malinyane a ntseng a khoesoa, ea fokotsa litaba tsa MDA le hydrogen peroxide ho jejunum, ea ntlafatsa ts'ebetso ea mitochondrial, ea fokotsa khatello ea oxidative ho malinyane a kolobe, le ho khothaletsa nts'etsopele ea mala.

Ho eketsa tributyl glyceride e nang le dikotwana tse nyane ho ka eketsa bophahamo ba villus ba duodenum le jejunum haholo, ho eketsa dikahare tsa baktheria ya lactic acid ka hara cecum le ho fokotsa dikahare tsa Escherichia coli, ho ntlafatsa sebopeho sa dimela tsa mala a di-broiler, mme phello ya TB e nang le dikotwana tse nyane e betere ho feta ya TB e metsi. Ka lebaka la karolo e ikgethang ya rumen ho diphoofolo tse busolosang, ho na le ditlaleho tse mmalwa mabapi le ditlahare tsa tributyl glyceride ho diphoofolo tse busolosang.

Jwalo ka thepa ya matla ya mala, tributyrin e ka ntlafatsa le ho lokisa sebopeho le sebopeho sa mala ka katleho, ya ntlafatsa tshilo ya dijo le bokgoni ba ho monya mala, ya kgothaletsa ho ata ha dibaktheria tse molemo mala, ya ntlafatsa sebopeho sa dimela tsa mala, ya fokotsa karabelo ya kgatello ya oxidative ya diphoofolo, ya kgothaletsa ntshetsopele ya mala a diphoofolo, le ho netefatsa bophelo bo botle ba mmele.

Phuputso e fumane hore ho eketsoa ha metsoako eatributyrinle oli ea oregano kapa methyl salicylate lijong tsa likolobe tse khoesitsoeng li ka eketsa boleng ba V/C ba mala, tsa ntlafatsa sebopeho sa mala a likolobe tse khoesitsoeng, tsa eketsa bongata ba Li-Firmicutes haholo, tsa fokotsa bongata ba Proteus, Actinobacillus, Escherichia coli, jj., tsa fetola sebopeho sa limela tsa mala le metabolites, e leng se molemo bophelong ba mala a likolobe tse khoesitsoeng, 'me se ka nkela lithibela-mafu sebaka ha ho sebelisoa likolobe tse khoesitsoeng.

Ka kakaretso,tributyrinE na le mesebetsi e fapaneng ea baeloji e kang ho fana ka matla bakeng sa 'mele, ho boloka botsitso ba mala, ho laola sebopeho sa limela tsa mala, ho nka karolo liketsong tsa 'mele tsa ho itšireletsa mafung le metabolism, jj. E ka khothaletsa nts'etsopele ea mala a liphoofolo le ho ntlafatsa ts'ebetso ea kholo ea liphoofolo. Glyceryl tributylate e ka bolisoa ke pancreatic lipase ka maleng ho hlahisa butyric acid le glycerol, tse ka sebelisoang e le mohloli o sebetsang oa butyric acid ka maleng a liphoofolo. Ha e rarolle feela bothata ba hore butyric acid e thata ho e eketsa lijong ka lebaka la monko oa eona le ho feto-fetoha ha eona, empa hape e rarolla bothata ba hore butyric acid e thata ho kena ka maleng ka mpeng. Ke sebaka sa lithibela-mafu se sebetsang hantle haholo, se bolokehileng le se setala.

Leha ho le jwalo, dipatlisiso tsa hajwale mabapi le tshebediso yatributyl glyceridePhepong ea liphoofolo e fokola haholo, 'me lipatlisiso mabapi le bongata, nako, sebopeho le motsoako oa lefuba le limatlafatsi tse ling lia haella. Ho matlafatsa ts'ebeliso ea tributyl glyceride tlhahisong ea liphoofolo ho ke ke ha fana feela ka mekhoa e mecha ea tlhokomelo ea bophelo bo botle ba liphoofolo le thibelo ea mafu, empa hape ho na le bohlokoa bo boholo ba ts'ebeliso nts'etsopele ea li-antibiotic tse nkelang sebaka, ka menyetla e pharaletseng ea ts'ebeliso.