Tšebeliso ea Lithibela-mafu e le likhothaletso tsa kholo tlhahisong ea liphoofolo e ntse e hlahlojoa le ho nyatsuoa ke sechaba. Nts'etsopele ea ho hanyetsa libaktheria khahlanong le lithibela-mafu le ho hanyetsa likokoana-hloko tsa batho le liphoofolo tse amanang le tšebeliso e sa lokelang ea lithibela-mafu ke lintho tse ka sehloohong tse tšoenyang.

Linaheng tsa EU, tšebeliso ea lithibela-mafu bakeng sa ho ntlafatsa tlhahiso ea liphoofolo e thibetsoe. Amerika, Ntlo ea Baemeli ba Mokhatlo oa Amerika e etsang melao e amohetse qeto sebokeng sa eona sa selemo le selemo ka Phuptjane e khothalletsang hore tšebeliso ea lithibela-mafu "e seng ea phekolo" liphoofolong e felisoe kapa e felisoe. Tekanyo ena e bua ka ho khetheha ka lithibela-mafu tse fuoang batho le tsona. E batla hore mmuso o felise tšebeliso e feteletseng ea lithibela-mafu liphoofolong, o atolose letšolo la mokhatlo la ho fokotsa ho hanyetsa ha batho meriana e pholosang bophelo. Tšebeliso ea lithibela-mafu tlhahisong ea liphoofolo e ntse e hlahlojoa ke mmuso 'me mehato ea ho laola ho hanyetsa lithethefatsi e ntse e ntlafatsoa. ​​Canada, tšebeliso ea Carbadox hajoale e ntse e hlahlojoa ke Health Canada 'me e tobane le thibelo e ka bang teng. Ka hona, ho hlakile hore tšebeliso ea lithibela-mafu tlhahisong ea liphoofolo e tla fokotseha le ho feta 'me mekhoa e meng ea ho khothalletsa kholo ea lithibela-mafu e hloka ho batlisisoa le ho sebelisoa.

Ka lebaka leo, ho ntse ho etsoa lipatlisiso khafetsa ho ithuta mekhoa e meng ea ho nkela lithibela-mafu sebaka. Mekhoa e meng e ntseng e ithutoa e fapana ho tloha litlama, li-probiotic, li-prebiotic le li-acid tsa organic ho ea ho li-supplement tsa lik'hemik'hale le lisebelisoa tsa taolo. Lithuto tse ngata li bontšitse hore formic acid e sebetsa hantle khahlanong le libaktheria tse bakang mafu. Leha ho le joalo, ts'ebetsong, ka lebaka la mathata a ho sebetsana, monko o matla le mafome ho lisebelisoa tsa ho lokisa lijo le tsa ho fepa le ho noa, tšebeliso ea eona e lekanyelitsoe. Ho hlōla mathata, potassium diformate (K-diformate) e fumane tlhokomelo e le mokhoa o mong oa formic acid hobane e bonolo ho e sebetsana le eona ho feta acid e hloekileng, ha e ntse e bontšitsoe e sebetsa hantle ho ntlafatseng ts'ebetso ea kholo ea likolobe tse nooang le tse holang. Phuputso e entsoeng ke bafuputsi Univesithing ea Temo ea Norway (J. Anim. Sci. 2000. 78:1875-1884) e bontšitse hore tlatsetso ea potassium diformate lijong maemong a 0.6-1.2% e ntlafalitse ts'ebetso ea kholo, boleng ba setopo le polokeho ea nama likolobeng tse holang ntle le litlamorao tse mpe boleng ba nama ea kolobe e utloang. Ho boetse ho bontšitsoe hore ho fapana lepotassium diformate Tlatsetso ea Ca/Na-formate ha ea ka ea ba le litlamorao ho hang kholong le boleng ba setopo.

Phuputsong ena, ho entsoe liteko tse tharo kaofela. Tekong ea pele, likolobe tse 72 (boima ba 'mele ba pele ba 23.1 kg le boima ba 'mele ba 104.5 kg) li ile tsa abeloa mekhoa e meraro ea ho phekola (Taolo, 0.85% Ca/Na-formate le 0.85% potassium-diformate). Liphetho li bontšitse hore lijo tsa K-diformate li ekelitse keketseho ea karolelano ea letsatsi le letsatsi ea keketseho (ADG) empa ha lia ka tsa ama karolelano ea tekanyo ea lijo tsa letsatsi le letsatsi (ADFI) kapa karolelano ea keketseho/fepa (G/F). Sekhahla sa nama e se nang mafura kapa mafura ha sea ka sa angoa ke potassium -diformate kapa Ca/Na-formate.

Tekong ea bobeli, likolobe tse 10 (BW ea pele: 24.3 kg, BW ea ho qetela: 85.1 kg) li sebelisitsoe ho ithuta phello ea K-diformate ts'ebetsong le boleng ba kutlo ba nama ea kolobe. Likolobe tsohle li ne li fepuoa ka mokhoa o lekanyelitsoeng 'me li fepuoa lijo tse tšoanang ntle le ho eketsa 0.8% K-diformate sehlopheng sa kalafo. Liphetho li bontšitse hore ho eketsa K-diformate lijong ho eketsa ADG le G/F, empa ha hoa ka ha ama boleng ba kutlo ba nama ea kolobe.

Tekong ea tse tharo, likolobe tse 96 (BW ea pele: 27.1 kg, BW ea ho qetela: 105kg) li ile tsa abeloa mekhoa e meraro ea phekolo ea lijo, e nang le 0, 0.6% le 1.2% K-diformate ka ho latellana, ho ithuta phello ea ho tlatsetsa.K-diformatelijong tse mabapi le ts'ebetso ea kholo, litšobotsi tsa setopo le microflora ea tšilo ea lijo. Liphetho li bontšitse hore ho tlatsetsoa ha K-diformate boemong ba 0.6% le 1.2% ho ekelitse ts'ebetso ea kholo, ho fokotsa mafura le peresente e ntlafetseng ea boima ba 'mele. Ho fumanoe hore ho eketsa K-diformate ho fokotsa palo ea li-coliform tšilong ea lijo ea likolobe, ka hona, ho ntlafatsa polokeho ea nama ea kolobe.